PubMed Studies
209
PubChem CID
About
Increases phosphocreatine stores in muscle — rapid ATP resynthesis during high-intensity exercise; reduces fatigue; may support cognitive function
How it works (mechanism of action)
Most evidence-based sports supplement. Very popular in France among athletes (Eric Favre, Pileje Sport, Solgar). Enhances strength, power and muscle mass. 5g/day protocol.
📊 Effectiveness
Muscle strength
Evidence Grade A · 72 studies · n=9,840 · Meta-analysis available
Exercise performance
Evidence Grade A · 58 studies · n=7,240 · Meta-analysis available
Cognitive function
Evidence Grade B · 9 studies · n=480
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Consult a healthcare professional before use if pregnant, breastfeeding, taking prescription medications, or if you have a medical condition. Keep out of reach of children.