SAFE
Copper gluconate
Copper gluconate
Possibly Safe
V2 Verified
Minerals & Trace Elements
PubMed Studies
4
PubChem CID
About
Highly bioavailable copper salt for deficiency supplementation. Copper essential for cytochrome c oxidase, superoxide dismutase, and collagen synthesis.
How it works (mechanism of action)
Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.
⚖️ Regulatory Status
⚠️
EU — Restricted
EFSA UL: 5mg/day elemental copper. Hepatotoxic at high doses. Wilson's disease absolute contraindication. [source ↗]
📊 Effectiveness
Anaemia
Evidence Grade A · 18 studies · n=2,800 · Meta-analysis available
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Wilson disease: ABSOLUTELY CONTRAINDICATED. Copper excess: hepatotoxicity, haemolytic anaemia. UL: 10mg/day adults. Zinc-copper antagonism: high-dose zinc supplements (>40mg/day) deplete copper — supplementation needed. Symptom of deficiency: anaemia, neutropenia, neurological problems.
🇪🇺 EU Health Claims Status
Art.13(1)
✓ AuthorisedThe claim may be used only for food which is at least a source of copper as referred to in the claim SOURCE OF [NAME OF VITAMIN/S] AND/OR [NAME OF MINERAL/S] as listed in the Annex to Regulation (EC) No 1924/2006.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedThe claim may be used only for food which is at least a source of copper as referred to in the claim SOURCE OF [NAME OF VITAMIN/S] AND/OR [NAME OF MINERAL/S] as listed in the Annex to Regulation (EC) No 1924/2006
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedThe claim may be used only for food which is at least a source of copper as referred to in the claim SOURCE OF [NAME OF VITAMIN/S] AND/OR [NAME OF MINERAL/S] as listed in the Annex to Regulation (EC) No 1924/2006.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedThe claim may be used only for food which is at least a source of copper as referred to in the claim SOURCE OF [NAME OF VITAMIN/S] AND/OR [NAME OF MINERAL/S] as listed in the Annex to Regulation (EC) No 1924/2006.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedThe claim may be used only for food which is at least a source of copper as referred to in the claim SOURCE OF [NAME OF VITAMIN/S] AND/OR [NAME OF MINERAL/S] as listed in the Annex to Regulation (EC) No 1924/2006.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedThe claim may be used only for food which is at least a source of copper as referred to in the claim SOURCE OF [NAME OF VITAMIN/S] AND/OR [NAME OF MINERAL/S] as listed in the Annex to Regulation (EC) No 1924/2006.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedThe claim may be used only for food which is at least a source of copper as referred to in the claim SOURCE OF [NAME OF VITAMIN/S] AND/OR [NAME OF MINERAL/S] as listed in the Annex to Regulation (EC) No 1924/2006.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedThe claim may be used only for food which is at least a source of copper as referred to in the claim SOURCE OF [NAME OF VITAMIN/S] AND/OR [NAME OF MINERAL/S] as listed in the Annex to Regulation (EC) No 1924/2006.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
🏷️ Other Names
Copper gluconate