SAFE

Collagen Type II (Undenatured)

collagen-type-ii-undenatured
Possibly Safe V1 Verified
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Upper Safe Limit
Chicken-derived — avoid in poultry allergy.
PubChem CID
About

Oral tolerance mechanism — UC-II trains regulatory T-cells to reduce autoimmune attack on cartilage collagen; distinct mechanism from hydrolysed collagen

How it works (mechanism of action)

Used for osteoarthritis and joint pain. 40mg/day UC-II superior to glucosamine+chondroitin in some trials. Growing in French pharmacy. Pileje, Solgar joint formulas.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Consult a healthcare professional before use if pregnant, breastfeeding, taking prescription medications, or if you have a medical condition. Keep out of reach of children.

Updated: 2026-04-02
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