SAFE

Coenzyme A

Coenzyme A precursors (CoA)
Possibly Safe V1 Verified Specialty Nutrients
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PubMed Studies
649
PubChem CID
About

Coenzyme A precursors (pantethine, phosphopantetheine) enhance CoA synthesis for fatty acid metabolism. Used for cholesterol and triglyceride management.

How it works (mechanism of action)

Provides targeted nutritional substrate or pharmacological activity for specific biochemical pathways not adequately supported by standard dietary intake. Mechanism involves enzyme cofactor provision, receptor modulation, or membrane structural modification.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Very limited human data on pure CoA supplementation. Pantethine is the standard supplement form (see Pantothenic Acid).

🇪🇺 EU Health Claims Status
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food has not been substantiated.
Regulation EU 1924/2006 · ART13 1
🏷️ Other Names
Coenzyme A precursors (CoA)
Updated: 2026-04-11
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