SAFE
Cnidium Monnieri
Cnidium monnieri (She Chuang Zi)
Possibly Safe
V1 Verified
TCM Herbs
PubMed Studies
480
About
Cnidium seeds contain osthole and coumarins with testosterone-like and antimicrobial effects.
How it works (mechanism of action)
Acts via multiple pharmacodynamic mechanisms consistent with Traditional Chinese Medicine polypharmacology. Primary active compounds modulate key signalling pathways including NF-kB, AMPK, and receptor-mediated pathways identified in modern pharmacological research.
📊 Effectiveness
Sexual dysfunction support
Evidence Grade C · 4 studies · n=280
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Coumarin content: anticoagulant interaction. Limited Western clinical data.
🏷️ Other Names
Cnidium monnieri (She Chuang Zi)