SAFE
Clove Extract
Syzygium aromaticum standardised eugenol
Likely Safe
V1 Verified
Anti-inflammatory Herbs
PubMed Studies
2
About
Clove standardised to eugenol with COX-inhibiting, antimicrobial, antifungal, and local anaesthetic effects.
How it works (mechanism of action)
Inhibits key inflammatory enzymes (COX-1/2, 5-LOX) or transcription factors (NF-kB, AP-1) reducing prostaglandin, leukotriene, and cytokine production. Some activate PPAR-gamma nuclear receptor mediating anti-inflammatory gene transcription.
👥 Safety by Population
🚫 Contraindications & Warnings
Anticoagulant interaction: eugenol antiplatelet. Dental applications well documented.
🏷️ Other Names
Syzygium aromaticum standardised eugenol