SAFE
Cissus Quadrangularis
Cissus quadrangularis (bone and joint)
Possibly Safe
V1 Verified
Sports Nutrition
PubMed Studies
12
About
Phytosterols and ketosteroids for bone healing, joint repair, and pain reduction in athletes.
How it works (mechanism of action)
Enhances exercise performance via substrate provision, haemodynamic effects (vasodilation via nitric oxide), or anabolic/anti-catabolic signalling (mTOR activation). Reduces exercise-induced oxidative stress and inflammatory cytokine production.
📊 Effectiveness
Joint healing
Evidence Grade B · 8 studies · n=640
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Limited long-term data. Drug interactions unknown. Pregnancy: avoid.
🏷️ Other Names
Cissus quadrangularis (bone and joint)