SAFE
Chrysin
Chrysin (aromatase inhibitor flavone)
Possibly Safe
V1 Verified
Mens Health
PubMed Studies
10
PubChem CID
About
Flavone that inhibits aromatase in vitro. Used for testosterone support. Oral bioavailability very poor.
How it works (mechanism of action)
Inhibits 5-alpha-reductase converting testosterone to DHT or acts as competitive DHT-androgen receptor antagonist. May modulate LH receptor signalling to support testosterone production. Anti-oestrogenic effects possible via aromatase inhibition.
📊 Effectiveness
Testosterone support
Evidence Grade C · 4 studies · n=280
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Poor bioavailability limits efficacy. No significant drug interactions documented. Generally safe.
🏷️ Other Names
Chrysin (aromatase inhibitor flavone)