⛔
Regulatory ban. This ingredient is banned or restricted in one or more countries. See Regulatory Status below.
SAFE
Chromium chloride
Chromium(III) chloride
Possibly Safe
V2 Verified
Minerals & Trace Elements
PubMed Studies
11
PubChem CID
About
Inorganic chromium(III) salt. Lower bioavailability than organic chromium forms. Used as reference form in chromium research.
How it works (mechanism of action)
Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.
⚖️ Regulatory Status
⛔
CH — Banned
Swissmedic banned kava in Switzerland due to hepatotoxicity.
⛔
DE — Banned
BfArM banned kava-containing products in Germany in 2002 due to hepatotoxicity risk. Cases of liver failure and death reported.
⛔
US — Banned
FDA issued warning letter against oral comfrey products. Contains pyrrolizidine alkaloids causing liver damage.
⚠️
CN — Restricted
NMPA China — berberine (berberine hydrochloride) registered as pharmaceutical (OTC drug) for specific indications. Not permitted as general health food ingredient at pharmaceutical doses.
⚠️
EU — Restricted
EFSA (2010) — genotoxicity concerns. Maximum dose levels apply. Several EU member states have restricted high-dose products.
⚠️
FR — Restricted
ANSES (2013) — maximum dose restrictions following EFSA genotoxicity concerns.
⚠️
IT — Restricted
Italian Ministry of Health — berberine supplements restricted to max 10mg/day without medical supervision.
💊
AU — Prescription only
DHEA is scheduled as a prescription-only medicine in Australia (Schedule 4).
💊
CA — Prescription only
DHEA is a controlled substance in Canada, available by prescription only.
👥 Safety by Population
🚫 Contraindications & Warnings
Less bioavailable than chromium picolinate or nicotinate. Same chromium UL considerations. Generally safe at supplement doses.
🏷️ Other Names
Chromium(III) chloride