SAFE
Chicory Root Extract
Cichorium intybus standardised
Likely Safe
V1 Verified
Liver Herbs
PubMed Studies
2
About
Chicory root provides inulin (prebiotic), bitter compounds (lactucopicrin), and anti-inflammatory effects for liver and digestive support.
How it works (mechanism of action)
Provides hepatoprotective effects via antioxidant enzyme induction (GPx, SOD), NF-kB suppression reducing hepatocyte apoptosis, and cytochrome P450 modulation. Choleretic action stimulates bile flow and composition benefiting lipid digestion and hepatic detoxification.
📊 Effectiveness
Gut microbiome
Evidence Grade B · 18 studies · n=2,200
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Allergy to Asteraceae. GI effects from inulin. Pregnancy: avoid medicinal doses.
🇪🇺 EU Health Claims Status
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this claimed effect for this food is not a beneficial physiological effect as required by the Regulation.
Regulation EU 1924/2006 · ART13 1
🏷️ Other Names
Cichorium intybus standardised