SAFE
Cellulose gum
Sodium carboxymethylcellulose (CMC, E466)
Possibly Safe
V2 Verified
Excipients & Additives
PubMed Studies
1
About
Water-soluble cellulose derivative used as thickener, binder, and stabiliser. E466 (sodium CMC). GRAS. Used in weight management products as a bulk-forming agent. Laxative at high doses.
How it works (mechanism of action)
Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.
👥 Safety by Population
🚫 Contraindications & Warnings
Mild laxative at high doses. May reduce absorption of some drugs (chelation). Corn-derived substrate: corn allergen consideration (trace). Generally safe. GRAS.
🏷️ Other Names
Sodium carboxymethylcellulose (CMC, E466)