SAFE
Celery Seed Anti-inflammatory
Apium graveolens seed standardised
Possibly Safe
V1 Verified
Anti-inflammatory Herbs
PubMed Studies
880
About
Celery seed containing 3nB (3-n-butylphthalide) with anti-inflammatory, uricosuric (gout), and blood pressure-lowering effects.
How it works (mechanism of action)
Inhibits key inflammatory enzymes (COX-1/2, 5-LOX) or transcription factors (NF-kB, AP-1) reducing prostaglandin, leukotriene, and cytokine production. Some activate PPAR-gamma nuclear receptor mediating anti-inflammatory gene transcription.
👥 Safety by Population
🚫 Contraindications & Warnings
Pregnancy: avoid medicinal doses. Allergy to Apiaceae. Photosensitivity.
🏷️ Other Names
Apium graveolens seed standardised