PubMed Studies
280
About
Contains sanguinarine and chelidonine similar to greater celandine. Used in Native American medicine for liver disorders.
How it works (mechanism of action)
Provides hepatoprotective effects via antioxidant enzyme induction (GPx, SOD), NF-kB suppression reducing hepatocyte apoptosis, and cytochrome P450 modulation. Choleretic action stimulates bile flow and composition benefiting lipid digestion and hepatic detoxification.
👥 Safety by Population
🚫 Contraindications & Warnings
Limited safety data. Hepatotoxicity potential. Not for routine use.
🏷️ Other Names
Stylophorum diphyllum