SAFE
Caffeic Acid
Caffeic acid 3,4-dihydroxycinnamic
Likely Safe
V1 Verified
Polyphenols
PubMed Studies
40
PubChem CID
About
From coffee, propolis, and plants with antioxidant, antimicrobial, and anti-inflammatory properties.
How it works (mechanism of action)
Acts as direct free radical scavenger and indirect antioxidant via Nrf2/ARE pathway activation. Modulates inflammatory signalling via NF-kB and AP-1 inhibition. Interacts with kinase pathways (MAPK, PI3K/Akt, mTOR) and epigenetic regulators relevant to anti-ageing and disease prevention.
👥 Safety by Population
🚫 Contraindications & Warnings
Very safe at dietary doses.
🏷️ Other Names
Caffeic acid 3,4-dihydroxycinnamic