SAFE
Burdock Root Extract
Arctium lappa standardised
Possibly Safe
V1 Verified
Liver Herbs
PubMed Studies
680
About
Burdock root with inulin, phenolic acids, and quercetin for liver support, skin conditions, and blood purification.
How it works (mechanism of action)
Provides hepatoprotective effects via antioxidant enzyme induction (GPx, SOD), NF-kB suppression reducing hepatocyte apoptosis, and cytochrome P450 modulation. Choleretic action stimulates bile flow and composition benefiting lipid digestion and hepatic detoxification.
📊 Effectiveness
Liver and skin support
Evidence Grade C · 6 studies · n=380
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Allergy to Asteraceae. Limited clinical data. Generally well tolerated.
🏷️ Other Names
Arctium lappa standardised