SAFE
Bupleurum Falcatum
Bupleurum falcatum (Chai Hu)
Possibly Safe
V1 Verified
TCM Herbs
PubMed Studies
880
About
Contains saikosaponins with anti-inflammatory, hepatoprotective, and immune-modulating effects.
How it works (mechanism of action)
Acts via multiple pharmacodynamic mechanisms consistent with Traditional Chinese Medicine polypharmacology. Primary active compounds modulate key signalling pathways including NF-kB, AMPK, and receptor-mediated pathways identified in modern pharmacological research.
📊 Effectiveness
Liver support
Evidence Grade B · 8 studies · n=640
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Hepatotoxicity: rare reports. Interstitial pneumonitis: case reports. Autoimmune: caution.
🏷️ Other Names
Bupleurum falcatum (Chai Hu)