SAFE

Boldo Leaf

Peumus boldus
Possibly Safe V1 Verified Herbs & Botanicals
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PubMed Studies
480
About

Boldo leaf contains boldine with choleretic (bile flow stimulating), hepatoprotective, and antiparasitic effects. Used in South American traditional medicine.

How it works (mechanism of action)

Contains bioactive phytochemicals (alkaloids, terpenoids, polyphenols, or glycosides) modulating cellular signalling pathways. Primary mechanisms include enzyme inhibition, receptor modulation, and transcription factor activation relevant to documented clinical indications.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Liver or bile duct obstruction: avoid. Pregnancy: avoid. Boldine is potentially fetotoxic at high doses.

🏷️ Other Names
Peumus boldus
Updated: 2026-04-02
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