SAFE

Black Cohosh Extract

Actaea racemosa (2.5% triterpene glycosides)
Possibly Safe V1 Verified Womens Health
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PubMed Studies
12
About

Standardised black cohosh for menopausal hot flashes, night sweats, and mood symptoms.

How it works (mechanism of action)

Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.

⚖️ Regulatory Status
⚠️
EU — Restricted
EMA restricts to max 6 months continuous use due to rare but serious hepatotoxicity cases. Liver enzyme monitoring recommended with prolonged use.
👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Hepatotoxicity: rare but documented. Limit to 6 months. Liver function: monitor.

🏷️ Other Names
Actaea racemosa (2.5% triterpene glycosides)
Updated: 2026-04-11
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