SAFE

Bacillus Coagulans

Bacillus coagulans (spore probiotic)
Likely Safe V1 Verified Gut Health
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PubMed Studies
57
About

Heat-stable spore probiotic surviving stomach acid and antibiotics. Used for IBS, diarrhoea, and immunity.

How it works (mechanism of action)

Provides substrate for beneficial gut bacteria fermentation or directly modulates intestinal epithelial cell function. Produces or stimulates short-chain fatty acids (propionate, butyrate, acetate) providing colonocyte energy and modulating immune tolerance via GPR41/43 activation.

📊 Effectiveness
IBS symptoms
Evidence Grade B · 12 studies · n=1,600
Possibly Effective

Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralLikely safeNo established UL
🚫 Contraindications & Warnings

Very safe. Shelf stable without refrigeration. Widely used in shelf-stable probiotics.

🇪🇺 EU Health Claims Status
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
🏷️ Other Names
Bacillus coagulans (spore probiotic)
Updated: 2026-04-02
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