⚠️
Major drug interaction. This ingredient has clinically significant drug interactions. See Drug Interactions below before use.
SAFE
Astragalus Polysaccharides
Astragalus polysaccharides (APS)
Likely Safe
V1 Verified
TCM Herbs
PubMed Studies
3
About
Purified Astragalus polysaccharides with immune-modulating and anti-tumour activity.
How it works (mechanism of action)
Acts via multiple pharmacodynamic mechanisms consistent with Traditional Chinese Medicine polypharmacology. Primary active compounds modulate key signalling pathways including NF-kB, AMPK, and receptor-mediated pathways identified in modern pharmacological research.
📊 Effectiveness
Immune modulation
Evidence Grade A · 18 studies · n=2,800 · Meta-analysis available
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Autoimmune: caution. Immunosuppressant interaction.
💊 Drug Interactions (4)
🔴 Cyclosporine / Tacrolimus
MajorImmunosuppressants
Management: Contraindicated in transplant patients.
🟡 Cyclophosphamide
ModerateChemotherapy
Management: Discuss with oncologist before use during chemotherapy.
⚪ Warfarin
MinorAnticoagulants
Management: Monitor INR at high doses.
⚪ Insulin
MinorAntidiabetics
Management: Monitor blood glucose.
🏷️ Other Names
Astragalus polysaccharides (APS)