PubMed Studies
52
PubChem CID
About
Alpha-ketoglutarate (AKG) is a key intermediate in the Krebs cycle. Used for anti-ageing, muscle recovery, wound healing, and longevity research.
How it works (mechanism of action)
Serves as building block for protein synthesis or direct precursor for neurotransmitters, hormones, and enzymatic cofactors. Participates in nitrogen metabolism, energy production, and cellular signalling pathways relevant to studied health outcomes.
👥 Safety by Population
🚫 Contraindications & Warnings
Limited long-term human data. Generally well tolerated.