SAFE
Alpha-cyclodextrin
α-Cyclodextrin (dietary fibre, E458)
Likely Safe
V2 Verified
Carbohydrates & Fibers
PubMed Studies
21
PubChem CID
About
Six-glucose ring cyclodextrin with dietary fibre characteristics. Reduces fat and carbohydrate absorption when taken with meals. E458. GRAS. Very low glycaemic impact.
How it works (mechanism of action)
Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.
👥 Safety by Population
🚫 Contraindications & Warnings
GI effects (gas, bloating) at higher doses. May reduce fat-soluble vitamin absorption. Generally safe. See Phase 2 excipients for full cyclodextrin profile.
🇪🇺 EU Health Claims Status
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ AuthorisedNon-compliance with the Regulation because on the basis of the scientific evidence assessed, this food is not sufficiently characterised for a scientific assessment of this claimed effect and the claim could not therefore be substantiated.
Regulation EU 1924/2006 · ART13 1
🏷️ Other Names
α-Cyclodextrin (dietary fibre, E458)
