SAFE

Alpha-cyclodextrin complexes

α-Cyclodextrin (6-glucose ring)
Possibly Safe V2 Verified Specialty Bioactives
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PubMed Studies
380
About

Alpha-cyclodextrin (6-membered ring glucose polymer). GRAS. Dietary fibre characteristics — fermented by colonic bacteria. Reduces cholesterol absorption at food-level doses.

How it works (mechanism of action)

Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

GRAS. Dietary fibre/prebiotic effects at food doses. GI gas and bloating. Generally safe. Cholesterol absorption reduction.

🇪🇺 EU Health Claims Status
Art.13(1)
✓ Authorised
The claim may be used for food which contains at least 5 g of alpha-cyclodextrin per 50 g of starch in a quantified portion as part of the meal. In order to bear the claim information shall be given to the consumer that the beneficial effect is obtained by consuming the alpha-cyclodextrin as part of the meal.
Regulation EU 1924/2006 · ART13 1
Art.13(1)
✓ Authorised
Non-compliance with the Regulation because on the basis of the scientific evidence assessed, the evidence provided is insufficient to substantiate this claimed effect for this food.
Regulation EU 1924/2006 · ART13 1
🏷️ Other Names
α-Cyclodextrin (6-glucose ring)
Updated: 2026-04-02
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