SAFE

Acetyl-L-Carnitine Arginate

ALCAR arginate dihydrochloride
Likely Safe V1 Verified Nootropics
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PubMed Studies
480
PubChem CID
About

Patented ALCAR form with arginate for enhanced nerve growth factor stimulation.

How it works (mechanism of action)

Enhances cognitive function via cholinergic system activation, cerebrovascular blood flow improvement, or neuroplasticity enhancement via BDNF/NGF upregulation. Neuroprotective mechanisms include antioxidant activity and reduction of excitotoxic glutamate signalling.

📊 Effectiveness
Cognitive function
Evidence Grade B · 10 studies · n=880
Possibly Effective

Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional

👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralLikely safeNo established UL
🚫 Contraindications & Warnings

Similar safety to standard ALCAR. Limited comparative studies.

🏷️ Other Names
ALCAR arginate dihydrochloride
Updated: 2026-04-11
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