SAFE
Acetyl Carnitine Energy
ALCAR energy formula
Likely Safe
V1 Verified
Energy Herbs
PubMed Studies
2,200
PubChem CID
About
Acetyl-L-carnitine for cellular energy production, fatty acid beta-oxidation, cognitive function, and anti-ageing.
How it works (mechanism of action)
Activates mitochondrial biogenesis and electron transport chain efficiency via AMPK/PGC-1alpha pathway. Modulates adenosine receptors or phosphodiesterase to regulate cellular cAMP/cGMP energy signalling. Normalises adrenal cortisol and catecholamine responses to physical and psychological stress.
📊 Effectiveness
Fatigue and cognitive decline
Evidence Grade B · 12 studies · n=1,400
Evidence grades: A=Strong RCT evidence · B=Good clinical trials · C=Limited trials · D=Preliminary/traditional
👥 Safety by Population
🚫 Contraindications & Warnings
Well tolerated. Possible increased bleeding. Thyroid interaction.
🏷️ Other Names
ALCAR energy formula