SAFE

Acesulfame potassium

Acesulfame-K (E950)
Possibly Safe V2 Verified Carbohydrates & Fibers
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PubMed Studies
7
PubChem CID
About

Non-nutritive synthetic sweetener 200x sweeter than sucrose. E950. Heat-stable. Widely used in combination with sucralose. FDA-approved. Safety studied for decades.

How it works (mechanism of action)

Acts on cellular signalling pathways relevant to the documented clinical indications. Contains bioactive compounds with enzyme-modulating, receptor-binding, or antioxidant properties studied in peer-reviewed literature.

⚖️ Regulatory Status
⚠️
EU — Restricted
EU maximum 800mg/day from supplements. Higher doses of potassium salts can cause cardiac arrhythmia. Must not be combined with potassium-sparing diuretics or ACE inhibitors without medical supervision.
👥 Safety by Population
PopulationSafety RatingMax Safe Dose
GeneralPossibly safeNot established
PregnancyPossibly safeNot established
ElderlyPossibly safeNot established
🚫 Contraindications & Warnings

Phenylketonuria: does not contain phenylalanine (unlike aspartame). Animal studies at supraphysiological doses suggested possible gut microbiome effects — not confirmed in humans at food use levels. Generally considered safe. Pregnant women: prefer to minimise non-nutritive sweetener use.

🏷️ Other Names
Acesulfame-K (E950)
Updated: 2026-04-11
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